EVIDENCE OF EFFICACY FOR GUIDED IMAGERY FOR

CHILDREN AND ADOLESCENTS

UNDERGOING CHEMOTHERAPY


September, 2006


Scope of the Problem

According to the National Cancer Institute, approximately 9,510 American children were expected to be diagnosed with cancer in 2005; approximately 1,585 children are expected to die, one-third from leukemia, a condition for which chemotherapy is the most effective treatment (American Cancer Society, 2005).

Unfortunately, chemotherapy is associated with numerous side effects. Vomiting, nausea, fatigue, and depression are common after treatments. Other side effects are nerve pain, mouth sores, and pain upon touching or being touched (Hockenberry-Eaton, Barrera, et al, 1999). There are also significant behavioral effects.

Younger children’s behavioral distress usually decreases as treatment goes on, while adolescents’ tends to increase (Dolgin, Katz, et al, 1989).. Adolescents also tend to have more nausea and vomiting than their younger children (Dolgin, Katz, et al.). Failure to cooperate with medical recommendations is frequently a problem, with adolescents tending to be less compliant than young children (Spinetta, Masera, et al, 2002).

Severe side effects, and non-compliance because of those side effects, can lead to loss of time at school for the child, loss of time at work for the caregiver, and additional office visits to the doctor -- all of which contribute both to death and disability, and to the annual costs of cancer (U.S. Dept. Health & Human Services, 2000).


Research in Mind/Body Interventions for Chemotherapy

Nausea can occur both after treatment, and before treatments ("anticipatory nausea"). Children respond well to various mind-body techniques, including distraction, including breathing exercises and relaxation techniques (Williams, Schmideskamp, et al, 2006).

Hypnosis has been successful in reducing or eliminating both types of nausea in adults and children (Jacknow, Tschann, et al, 1994; Machioro, Azzarello, et al, 2000; Morrow and Morrell, 1982).
Relaxation training has also proven effective in reducing anticipatory nausea adults and children (Jacknow, Tschann, et al; Vasterling, Jankins, et al, 1993).

As early as 1982, a study reported that relaxation significantly reduced anticipatory nausea (Morrow and Morrell). In one pediatric study, the hypnosis group had less anticipatory nausea and lower need for anti-nausea medication during both the first and second courses of chemotherapy (Jacknow, Tschann, et al). Hypnosis, as well as distraction and relaxation, reduced both distress and nausea (Zeltzer, Dolgin, et al, 1991).

Patients’ well-being and ability to tolerate treatment are also enhanced by the use of guided imagery. Adult patients using guided imagery specifically geared toward chemotherapy reported a “significantly more positive experience” (Troesch, Rodhaver, et al, 1993).
Imagery is effective in pain relief, too.

Imagery, relaxation and a psychological approach called cognitive behavioral training can reduce the pain of certain chemotherapy side effects (Syrjala, Donaldson, et al, 1995). Relaxation and imagery can also relieve anxiety and depression by improving quality of life, and reducing side effects.

Breast cancer patients who used guided imagery and relaxation were more relaxed during chemotherapy, and had a better quality of life. This lead the study’s authors to conclude that relaxation and guided imagery were “simple, inexpensive and beneficial” for patients undergoing chemotherapy (Walker LG, Walker MB, et al, 1999). The National Cancer Institute (2001) has also recommended “relaxation therapy, guided imagery, hypnosis, music, and other techniques…to ease your child's discomfort and fear” before and during cancer procedures.


A pediatric guided imagery program can increase relaxation, coping skills, and compliance, and reduce anxiety, discomfort, and side effects of chemotherapy. A caregivers’ guided imagery program can enable parents and others involved in the care of the child to reduce their stress, and increase their relaxation and coping skills.

Conclusion

Relaxation with guided imagery is a safe, inexpensive intervention that can improve pediatric chemotherapy patients’ quality of life, reduce side effects, and help with anxiety and depression. This can help to improve compliance and lower incidents of stopping treatment before it is finished.

REFERENCES

American Cancer Society. Cancer Facts and Figures 2005. Atlanta: American Cancer Society; 2005 pg. 11. http://www.cancer.org/downloads/STT/CAFF2005f4PWSecured.pdf.
Accessed September, 2006.

Dolgin MJ, Katz ER, Zeltzer LK, Landsverk J. Behavioral distress in pediatric patients with cancer receiving chemotherapy.
Pediatrics. 1989 Jul;84(1):103-10.

Hockenberry-Eaton M, Barrera P, Brown M, Bottomley SJ, O’Neill JB. Pain Managent in Children with Cancer.
Texas Cancer Council. 1999
http://childcancerpain.org/contents/childpainmgmt.pdf Accessed September, 2006.

Jacknow DS, Tschann JM, Link MP, Boyce WT. Hypnosis in the prevention of chemotherapy-related nausea and vomiting in children: a prospective study.
J Dev Behav Pediatr. 1994 Aug; 15 (4): 258-64.

Marchioro G, Azzarello G, Viviani F, Barbato F, Pavanetto M, Rosetti F, Pappagallo GL, Vinante O. Hypnosis in the treatment of anticipatory nausea and vomiting in patients receiving cancer chemotherapy. Oncology. 2000 Aug; 59 (2): 100-4.

Morrow GR, Morrell C. Behavioral treatment for the anticipatory nausea and vomiting induced by cancer chemotherapy.
NEJM. 1982 307; 1476-80.

National Cancer Institute. Young People with Cancer: A Handbook for Parents. U.S. Department of Health and Human Services, 2001
http://www.nci.nih.gov/cancertopics/youngpeople
Accessed September, 2006.

Spinetta JJ, Masera G, Eden T, Oppenheim D, Martins AG, van Dongen-Melman J, Siegler et al. Refusal, Non-Compliance, and Abandonment of Treatment in Children and Adolescents with Cancer. A Report of the SIOP Working Committee on Phychosocial Issues in Pediatric Oncology.
Med Pediatr Oncol. 2002 38:114-117.

Syrjala KL, Donaldson GW, Davis MW, Kippes ME, Carr JE. Relaxation and imagery and cognitive-behavioral training reduce pain during cancer treatment: a controlled clinical trial.
Pain. 1995 Nov; 63 (2):189-98.

Troesch LM, Rodehaver CB, Delaney EA, Yanes B. The influence of guided imagery on chemotherapy-related nausea and vomiting.
Oncol Nurs Forum. 1993 Sep; 20 (8): 1179-85.

U.S. Department of Health and Human Services.
Healthy People 2010: Understanding and Improving Health. 2nd ed. Washington, DC: U.S. Government Printing Office, November 2000.
www.health.gov/healthypeople/Document/pdf/Volume1/
03Cancer.pdf
Accessed September, 2006.

Vasterling J, Jenkins RA, Tope DM, Burish TG. Cognitive distraction and relaxation training for the control of side effects due to cancer chemotherapy.
J Behav Med. 1993 Feb; 16 (1): 65-80.

Walker LG, Walker MB, Ogston K, Heys SD, Ah-See AK, Miller ID, Hutcheon AW, Sarkar TK, Eremin O. Psychological, clinical and pathological effects of relaxation training and guided imagery during primary chemotherapy. Br J Cancer. 1999 Apr; 80 (1-2): 262-8.

Williams PD, Schmideskamp J, Ridder EL, Williams AR.Symptom monitoring and dependent care during cancer treatment in children: pilot study. Cancer Nurs. 2006 May-Jun;29(3):188-97.

Zeltzer LK, Dolgin MJ, LeBaron S, LeBaron C. A randomized, controlled study of behavioral intervention for chemotherapy distress in children with cancer
. Pediatrics. 1991 Jul;88(1):34-42.

<< PREVIOUS PAGE